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JSSC 2012第4期Medical & Bio0.18μm

Magnetic Relaxation Detector for Microbead Labels Paul Peng Liu Student Member

一种基于0.18微米CMOS工艺的紧凑型磁弛豫微珠标签检测器,用于生物医学检测。
0.18μm CMOS, 16ms检测时间, 单4.5μm磁珠检测
磁弛豫检测微珠标签生物医学检测CMOS嵌入式电磁体
利用磁弛豫特征提高环境变化容忍度
嵌入式电磁体消除外部磁体需求
相关双采样与偏移伺服环路结合抑制检测偏移
Abstract
A compact and robust magnetic label detector for biomedical assays is implemented in 0.18- mC M O S .D e t e c t i o n relies on the magnetic relaxation signature of a microbead label for improved tolerance to enviro nmental variations and relaxed dynamic range requirement, elim inating the need for baseline calibration and reference sensors. The device includes embedded electromagnets to eliminate external magnets and reduce power dissipation. Correlated double sampling combined with offset ser