Track-and-Zoom Neural Analog-to-Digital Converter With Blind Stimulation Artifac

Abstract

Closed-loop neuromodulation for the treatment of neurological disorders requires monitoring of the brain activ- ity uninterruptedly even during neurostimulation. This article presents a bidirectional 32-channel CMOS neural interface that can record neural activity during stimulation. Each channel con- sists of a dc-coupled  2-modulated analog-to-digital converter (neural-ADC), which records slow potentials ( <0.1 Hz) while accommodating rail-to-rail dc offset using a spectrum-shaping front-end