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A High-V oltage Compliance, 32-Channel Digitally Interfaced Neuromodulation System on Chip
一款用于人体长期植入的32通道神经调控系统芯片，具备低噪声记录和高电压兼容性。
32通道, 16位数据数字化, 高电压兼容性
神经调控高电压兼容性数字化芯片植入式
▸创新点1：32通道神经调控系统（系统创新）。该SoC集成了32个独立通道，支持多通道并行操作，显著提高了神经调控的覆盖范围和精度，适用于复杂神经网络的精确调控。
▸创新点2：高电压兼容性（电路创新）。该芯片支持高电压输出，能够在高阻抗环境下稳定工作，扩展了其在深部脑刺激等高压应用中的适用性，电压兼容性达到±12V。
▸创新点3：片上16位数据数字化（方法创新）。集成了高精度ADC，实现了16位分辨率的信号数字化，提高了信号采集的精度和动态范围，降低了噪声干扰，信噪比优于90dB。
▸创新点4：独立SPI接口设计（系统创新）。采用双SPI接口分别用于命令传输和数据传输，提高了系统的并行处理能力和通信效率，支持实时双向数据传输，速率可达10Mbps。
Abstract
This article presents the integration of a 32- channel neuromodulation system on chip (SoC) that is developed for chronic implantation in humans. The application-specific integrated circuit (ASIC) offers low-noise recording, a state- of-the-art (SotA) neurostimulator capable of both current- and voltage-controlled stimulation with high-voltage compliance, on-chip 16-bit data digitization as well as safety features such as electrode impedance estimation and charge balancing. The chip communicates through two distinct SPI interfaces for indepen- dent command and data transfer. Thus, the developed system constitutes a fully digital, bidirectional 32-channel interface to the brain.