GalEPR A Galvanically Coupled Electron Paramagnetic Resonance Spectrometer for D

Abstract

This work presents a galvanically coupled electron paramagnetic resonance spectrometer (GalEPR) for deep tissue oximetry and hypoxia diagnosis. Current in vivo EPR spectroscopy directly trades between the operation frequency (equivalent to sensitivity) and the penetration depth due to tissue absorption. Prior art is limited to 1.2 GHz/15 mm and 9 GHz/2 mm. To address this issue, a 30-MHz clock is galvanically coupled through the body to minimize attenuation and up-converted to 14 GHz by a low-po