A 65-nm CMOS Fluorescence Sensor for Dynamic Monitoring of Living Cells Fatemeh

Abstract

Integrating silicon chips and live bacterial biosen- sors in a miniaturized “cell-silicon” system can enable a wide range of applications in smart medicine and environmental sensing. Such integrated systems need on-chip optical filtering in the wavelength range compatible with fluorescent proteins (FPs), which are the widely used signal reporters for bacterial biosen- sors. However, the operating range of the prior works falls short in detecting the FP signals. Here, we report a fully integrated