⚡ 本页包含 AI 生成的分析内容,仅供参考
该论文提出了一种用于小鼠体内实时血压监测的无线无电池植入式微系统,重量仅130mg,功耗300µW,解决了长期在体血压监测缺乏合适方案的问题。
Genetic engineering of mice DNA sequences, together with in vivo real-time blood pressure measurement is crucial for identifying an animal’s genetic variation susceptibility to cardiovascular-related diseases. However, there is no adequate solution for long-term in vivo blood pressure monitoring to date. Due to the small size of laboratory mice, a miniature, light-weight, wireless, batteryless, implantable microsystem is highly critical to capture accurate biological signals from an untethered animal in its natural habitat, thus eliminating stress and post-implant trauma-induced information distortion. Furthermore, miniaturization of a packaged system is essential for interfacing with a mouse’s arteries, which exhibit a small diameter of only 200µm, and is crucial for achieving a reliable sensor-artery contact for accurate measurement. The small artery renders intra-vascular stent-based blood-pressuresensing techniques infeasible. Remote RF powering has been widely used for
Peng Cong, Nattapon Chaimanonart, Wen H. Ko, Darrin J. Young
Case Western Reserve University, Cleveland, OH