Medical & Bio

*Equally Credited Authors (ECAs) Abstract A hydrogel-based single-culture dual-fluorescence sensor is presented for bioavailable phosphorus (P) detection. The sensor achieves 6.6fA sensitivity with a 15.5dB SNR and an ou

California, Los Angeles, CA, Kyushu University, Fukuoka, Japan 1 5 Abstract This paper presents a 0.62g light-weight battery-less sensor tag for continuous monitoring of plant stress. A wireless link at 920MHz powers the

Abstract Lab-on-CMOS platforms require joint sensing–manipulation capabilities for biosamples from single cells to organoids. Existing methods such as DEP, optical, and acoustic tweezers need external setups, continuous

Abstract The paper presents a 256-channel solid-state nanopore readout IC in 65nm CMOS. A new integrate-and-hold TIA cuts per-pore power and area >6× while achieving 1MHz BW and 193pArms at 10nA. Event detection with dyn

span (100Gauss) Ultra-fast scan (1400THz/s) EPR-on-a-Chip based on injection-locked phase detection, implemented in CMOS 22nm-FDSOI technology is presented. 14GHz coherent frequency generation and sensing signal down-con

Leilei Huang1, Chunqi Shi1, Yuhong Wei1, Yue Lu1, Ningzi Guan1, Haifeng Ye1, Jinghong Chen2, Runxi Zhang1 East China Normal University, Shanghai, China, 2University of Houston, Houston, TX *Equally Credited Authors (ECAs

can give insight into the operation of neurological circuits and provides opportunities to restore function in patients with nerve damage. Realtime activity data from specific, spatially distributed efferent nerves provi

of diseases affecting the nervous, circulatory, and endocrine systems [1-3,5]. Charging the battery embedded in IMDs using conductors poses the risks of infection and aversion to surgery, leading to the development of wi

invasiveness and complexity of the device-deployment process. In such miniaturization, the main bottleneck is wireless power and data transfer (WPDT), particularly the volume of the receiver (RX) coil. Conventionally, on

Electroceuticals that directly stimulate nerves are attracting attention as their effectiveness on various intractable diseases has been verified [1]. In such wireless implantable neurostimulators, miniaturizing the rece

*Equally Credited Authors (ECAs) The advancement of miniature implantable medical devices (IMDs) has made remarkable progress toward creating minimally invasive and broadly accessible therapeutic and monitoring solutions

The permittivity and conductivity of bioimpedance in tissues are governed by α, β, and γ dispersions, with biological features detectable in the tens of MHz range. Wideband spectroscopy is required in many applications i

technologies promise a paradigm shift to preventive, proactive, and accessible health care. Real-time and long-term imaging offers unprecedented insights into one’s body conditions, enabling constant monitoring of highri

Compared to its implant-based electrical counterpart, ultrasonic vagus nerve stimulation alters neuronal activity through mechanical ultrasound waves, emerging as a promising non-invasive therapy for managing drug-resist

electrostatic and piezoelectric actuators are crucial in small-scale electromechanical applications, but they significantly impact the overall system weight, especially in microrobotics [1,2,3]. These systems operate at

Haochen Zhang1, Wei-Han Yu1, Zhongyu Zhao1, Zhizhan Yang1, Ka-Fai Un1, Jun Yin1, Rui P. Martins1,2, Pui-In Mak1 University of Macau, Macau, China Instituto Superior Tecnico/University of Lisboa, Lisbon, Portugal 1 2 Sens

Aditya Yadav1, David Lloyd3, Nicolò Ferri4, Mark Bignell4, Daniele Di Nuzzo4, Phillip Nadeau1, Matthew Hayes4, Roman Trogan1 Analog Devices, Boston, MA Analog Devices, Limerick, Ireland 3 Analog Devices, San Jose, CA 4 E

developing millimeter-scale and micrometer-scale micro-robots. However, achieving autonomous motion within a CMOS die has remained a significant challenge. This difficulty stems from the need to integrate energy harvesti

such as TNF-alpha and IL-6, play a crucial role as biomarkers in the management of chronic diseases like autoimmune disorders, cardiovascular diseases, and cancer [1]. Since long-term monitoring of these cytokines is ess

species and concentrations is critical for a myriad of applications, including environmental protection, industry automation, public health monitoring, and bio-/chemical-security surveillance. For example, gas sensing in

low-concentration molecular biomarkers requires sending samples to centralized labs, leading to high costs and delays (Fig. 20.3.1). Recent developments in molecular diagnostics thus aim to enable point-of-care (POC) det

University of California, San Francisco, CA 1 ~60% of cancer patients undergo surgery to remove a primary tumor, and precise removal of all cancer cells is vital for optimal outcomes [1]. Microscopic clusters of cancer c

Energy-constraint wireless transceivers with wake-up receivers (WuRX) traditionally rely on an always-running clock (Fig. 20.11.1) for sampling incoming data and digital correlation, necessitating local oscillator calibr

Near fields, unencumbered by the restrictions imposed by diffraction limits, can be leveraged in high-resolution sub-wavelength imaging systems [1]. Utilizing the near-fields generated by arrays of mmWave and THz resonat

University of Tsukuba, Tsukuba, Japan 4 University of Southern California, Los Angels, CA 1 2 Miniaturizing and reducing the power consumption of multi-modal gas sensors with multiple channels can enable a wide array of

China 1 2 Capacitive touch systems play a crucial role in user interfaces across many applications, such as mobile devices, desktop PCs, and interactive whiteboards [1-6]. In capacitive touch systems, various sources of

become a prevalent use interaction method over the past decade, owing to their multi-touch capabilities and ease of use. There is a great demand for sub-display panels outside smartphones in emerging form-factor products

flagship smartphones thanks to their thin form factor. However, the touch sensor integrated within the display faces several technical challenges arising from large parasitic capacitance of the touch sensor [1]. A potenti

C&Tech, Seoul, Korea 1 2 With the rapid development of display technology, there is a growing demand for highcolor-depth, low-power, cost-effective, and compact source-driver ICs (SD-IC), which convert digital data to an

with digital-to-analog conversion (DAC) and signal drive into pixels, drastically impact image quality in displays. As the demand for higher spatial resolution to enhance visual realism grows, even in mobile displays, a

Eugene Hwang, Gerard O’Leary, Yu Huang, Mustafa Kanchwala, Mohammad Abdolrazzaghi, Chenxi Tang, Patty Liu, Yuan Sui, Xilin Liu, George Eleftheriades, José Zariffa, Roman Genov University of Toronto, Toronto, Canada The p

neural-recording devices get denser and generate more data [1], on-chip and online neural-signal processing becomes crucial to reduce the data-transmission power and enable real-time closed-loop applications with minimum

Gain Kim, Jong-Hyeok Yoon, Arup K. George, Junghyup Lee Daegu Gyeongbuk Institute of Science and Technology, Daegu, Korea Wearable devices rely on accurately read bio-potentials such as ECG, EEG, EMG, and EOG (ExG) to tr

Seungyeob Baik, Jaeha Kung, Ji-Woong Choi, Arup K. George, Junghyup Lee Daegu Gyeongbuk Institute of Science and Technology, Daegu, Korea Precise current measurements underpin emerging applications such as photoplethysmo

National University, Cheongju, Korea 4 Korea University Guro Hospital, Seoul, Korea 1 2 Retinal prosthesis (RP) systems-on-chip (SoC) for the treatment of age-related macular degeneration (AMD) and retinal pigment degene

Hanyang University, Seoul, Korea 4 SOSO H&C, Daegu, Korea 1 To overcome this limitation, a 10b DR-EPFL is proposed to have two CDAC loops of 6b coarse and 4b fine, where the fine CDAC is designed to provide equivalently

self-capacitance sensing has been mostly used for the following purposes: (1) to realize multi-touch on the matrix sensor, especially in full in-cell LCDs [1], and (2) to distinguish false touches at which water is dropp

interaction systems in mobile devices. In addition to traditional capacitive touch systems, a stylus is becoming mainstream, which is a very useful feature for large-sized tablet PCs [1]. However, wearable devices, which

and faster refresh rate displays, the nextgeneration TVs and gaming monitors are expected to accommodate 8K resolution with a refresh rate of 120Hz and beyond. In such display systems, about one thousand channels will be

Christophe Plantier, Emmanuel Rolland, Marc Gely, Giulia Usai, Claude Tabone, Gaël Pillonnet, Stéphanie Robinet, Sébastien Hentz CEA-Léti, Grenoble, France NanoElectroMechanical System (NEMS)-based resonator sensors are

Roswell Biotechnology, San Diego, CA metal are exposed by etching away a sacrificial 23µm×15µm “bond pad” to expose a common staging area for the electrodes of 4 adjacent pixels. The 50nm wide electrodes are patterned, t

Jongseok Park4, Dongwon Lee1, Mian Wang2, Sushila Maharjan2, Sagar Kumashi1, Jin Hao2, Yu Shrike Zhang2, Kevin Eggan5, Hua Wang1,6 Georgia Institute of Technology, Atlanta, GA Brigham and Women’s Hospital, Harvard Univer

Chris Van Hoof1,2, Jan Genoe1,2, Sebastian Haesler1,2,3,5, Georges Gielen1,2, Nick Van Helleputte1, Carolina Mora Lopez1 imec, Leuven, Belgium KU Leuven, Leuven, Belgium 3 Neuroelectronics Research Flanders, Leuven, Belg

Ting-Heng Lu1, Ling-Chia Chen1, I-Che Ou1, Sook-Kuan Lee2, Yen-Chi Chen2, Po-Hung Chen1, Chi-Te Liu2, Ying-Chih Liao2, Yu-Te Liao1 National Yang Ming Chiao Tung University, Hsinchu, Taiwan National Taiwan University, Tai

voltage VINT. Upon light illumination, the photocurrent through the drain of the MoS2 photo-FET in a given pixel discharges CP, and a counter records the total number of clock cycles (nCLK), until the voltage across CP r

Processing, Communication and Actuation Li Xu1, Maya Lassiter2, Xiao Wu1, Yejoong Kim1, Jungho Lee1, Makoto Yasuda3, Masaru Kawaminami4, Marc Miskin2, David Blaauw1, Dennis Sylvester1 University of Michigan, Ann Arbor, M

Aly Shoukry, Camilo Tejeiro, Chenxi Tang, Enver Kilinc, Jaimin Joshi, Parisa Sabetian, Samantha Unger, José Zariffa, Paul Yoo, Roman Genov University of Toronto, Toronto, Canada The peripheral nervous system (PNS) enable

of electronics into tissue-penetrating probes improves the signal quality and reduces parasitic effects for high-density recording of in vivo neural activity. In contrast to passive neural probes or devices implementing

Korea Aerospace Research Institute, Daejeon, Korea 1 2 Improving robustness to common-mode interference (CMI) is imperative for reliable two-electrode ECG recording. CMI degrades the signal quality in two ways. First, it

National University of Singapore, Singapore 1 2 *Equally-Credited Authors (ECAs) Bio-impedance (BioZ) is an important physiological parameter in wearable healthcare sensing. Besides the inherent cardiac and respiratory i