⚡ 本页包含 AI 生成的分析内容，仅供参考
本文提出了一种3×3.3mm的可配置γ光子能谱仪，用于精准放射引导的癌症切除手术。该器件旨在术中实时检测微小癌细胞团，降低复发风险。
University of California, San Francisco, CA 1 ~60% of cancer patients undergo surgery to remove a primary tumor, and precise removal of all cancer cells is vital for optimal outcomes [1]. Microscopic clusters of cancer cells are intraoperatively hard to visualize and are often left behind, significantly increasing the risk of cancer recurrence. Radioguided surgery (RGS) is one technique that has been shown to help prevent this [2]. This method involves conjugating a gamma photon (γ)-emitting radioisotope to a cancer-targeting molecule and administering this radioactive tracer intravenously to the patient before surgery where it preferentially binds to cancer cells. During surgery, a γ-sensing probe is used to locate areas with γ signal to remove all cancerous lesions, and since γ’s have superior tissue penetration properties compared to visible photons used in microscopy [3], deeper lesions can be sensed as well. State-of-theart γ probes show the benefit of RGS but lack the form-fact
Rahul Lall1, Youngho Seo1,2, Ali Niknejad1, Mekhail Anwar1,2
University of California, Berkeley, CA