⚡ 本页包含 AI 生成的分析内容，仅供参考
本文提出一种持续48天的表皮粘贴式生物电子设备，集成19fA分辨率的生物发光模拟前端与TDM-SAR校准及混合模式LED，实现针对1型糖尿病的闭环实时检测与精准治疗，解决了传统指尖采血和电化学方法无法连续监测及治疗的问题。
Leilei Huang1, Chunqi Shi1, Yuhong Wei1, Yue Lu1, Ningzi Guan1, Haifeng Ye1, Jinghong Chen2, Runxi Zhang1 East China Normal University, Shanghai, China, 2University of Houston, Houston, TX *Equally Credited Authors (ECAs) 1 Abstract Conventional management of type-1 diabetes (T1D) relies on finger-prick blood sampling or electrochemical methods, which prevent continuous monitoring and treatment. This paper presents a novel epidermal pasting bioelectronic device (PBD). The device integrates a 19fA- resolution bioluminescence analog front-end (BAFE) with TDM-SAR calibration and a hybridmode LED driver. It enables closed-loop realtime detection and precision treatment for T1D. The battery life reaches 48 days. Traditional type-1 diabetes (T1D) management primarily relies on finger-prick blood sampling or electrochemical method [1, 2], followed by manual administration of oral medications or injections, which limits realtime detection and precision treatment of T1D.
Xiaoyuan Wu*1, Kangjie Zhao*1, Mengyao Liu*1, Shixiang Ding1, Xuyang Li1, Yuri Lu1, Ruohan Wang1, Ziyan Zhao1, Liwen Qian1, Yang Yang1, Jing Wu1,