Mixed-Signal Integrated Circuits for Self-Contained Sub-Cubic Millimeter Biomedical Implants

📋 论文概要

该论文针对全无线微型植入式医疗设备的挑战，研究了混合信号集成电路用于自容式亚立方毫米生物医学植入体。通过活体兔子实验量化了组织对无线眼部植入体的电磁功率损失（4-5dB），并分析了2.4GHz工作频率的选择依据。

💡 主要创新点

• 通过活体动物实验（兔眼）量化了组织对无线植入体的电磁功率损耗（4-5dB），为植入体设计提供实测依据。
• 分析了电小天线效率及FCC分配频段，确定了2.4GHz作为最佳工作频率，克服了微型植入体的能量传输难题。
• 开发了适用于亚立方毫米尺度的混合信号集成电路，实现了自容式（无需外部电池或连线）的微型植入体方案。

🏷 关键词

📄 原文摘要

Purdue University, West Lafayette, IN Texas Instruments, Dallas, TX 2 Development of fully wireless miniature implantable medical devices is challenging due to inefficiencies of electrically small antennas and tissue-induced electromagnetic power loss. Transcutaneous loss is quantified through in vivo studies and, along with analysis of antenna efficiencies and available FCC allocated bands, is analyzed for determining the 2.4GHz operating frequency. Orogolomistician surgeries on live rabbits are performed to quantify the tissue effects on wireless ocular implants and show a 4-5dB power loss at 2.4GHz [1]. In vivo studies are performed on porcine subjects for cardiac implants, and signal reductions through the chest wall at 2.4GHz are measured to be 33-35dB [2]. The system, shown in Fig. 12.2.1, is designed and fabricated on the TI 130nm CMOS process. The wireless transmitter uses a complementary cross-coupled

👥 作者与机构

Eric Y Chow1, Sudipto Chakraborty2, William J. Chappell1, Pedro P. Irazoqui1