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ISSCC 2010Session 12 · EMERGING MEDICAL APPLICATIONSMedical & Bio

An Implantable 5mW/Channel Dual-Wavelength Optogenetic Stimulator for Therapeutic Neuromodulation Research

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📋 论文概要

该论文提出了一种植入式双波长光遗传刺激器,用于治疗性神经调控研究。它解决了传统电刺激在选择性调制特定神经群体和避免副作用方面的局限性,每个通道功耗仅5mW。

💡 主要创新点

核心指标
5mW/channel
重要性
发表年份
ISSCC 2010

🏷 关键词

光遗传学植入式刺激器双波长神经调控低功耗

📄 原文摘要

technology of many neurological therapies, electrical stimulation suffers from several drawbacks. Constraints on electrode geometry and placement can result in an inability to modulate specific neural populations, and stimulation of non-target networks can cause undesirable side-effects. Conducting electrodes in tissue can also restrict the level of tolerated EM exposure from modalities like MRI and electrosurgery, and large stimulation currents can undermine the ability to simultaneously sense underlying neural activity when implementing a closed-loop therapy system [1]. These drawbacks motivate the need for exploring alternative techniques to therapeutically modulate neural network activity. “Optogenetic” neuromodulation is a rapidly evolving technology wherein cellular

👥 作者与机构

Kunal Paralikar1, Peng Cong1, Wesley Santa1, David Dinsmoor1,

Bob Hocken2, Gordon Munns1, Jon Giftakis1, Timothy Denison1 1 Medtronic Technology, Minneapolis, MN Medtronic Technology, Tempe, AZ 2 While serving as the core

分类:Medical & Bio · 年份:ISSCC 2010