Palm NMR and One-Chip NMR 1 2 2 1

📋 论文概要

本文提出了手掌大小的核磁共振（NMR）系统和单芯片NMR方案，旨在解决传统NMR设备体积庞大、沉重且昂贵的问题，使其能够应用于便携式生物传感和医疗诊断。

💡 主要创新点

• 实现NMR系统的小型化，开发手掌大小的便携设备，降低对大型磁体和复杂收发器的依赖。
• 提出单芯片NMR架构，将磁体、样品线圈和RF收发器集成在一个芯片上，大幅缩小系统尺寸和成本。

🏷 关键词

📄 原文摘要

Cambridge, MA, T2 Biosystems, Cambridge, MA 2 3 Nuclear magnetic resonance, or NMR, is the energy exchange between an RF magnetic field and an atomic nucleus such as a hydrogen proton, which is a tiny bar magnet due to its spin. NMR has a broad array of powerful applications, including: biomolecule sensing (e.g., cancer marker detection), medical imaging, and oil detection. NMR instruments, however, are bulky, heavy, and expensive, and remain as specialized equipment in hospitals, industry, and laboratories. An NMR system consists of a magnet, a sample coil, and an RF transceiver, where the magnet is by far the largest component. As a larger-sized magnet yields a stronger NMR signal even for the same field strength, large magnets are used, hence the bulky size.

👥 作者与机构

Nan Sun , Tae-Jong Yoon , Hakho Lee , William Andress ,

Vasiliki Demas3, Pablo Prado3, Ralph Weissleder2, Donhee Ham1 1 Harvard University, Cambridge, MA, Massachusetts General Hospital, Harvard Medical School,