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本文提出了一种立方毫米级、能量自给的无线眼内压监测芯片，用于青光眼患者的连续眼内压监测。该芯片通过微型化设计和能量采集技术，实现了植入式长期监测，解决了传统单次测量无法捕捉眼内压波动的问题。
Yejoong Kim, Gyouho Kim, David Fick, Daeyeon Kim, Mingoo Seok, Kensall Wise, David Blaauw, Dennis Sylvester University of Michigan, Ann Arbor, MI Glaucoma is the leading cause of blindness, affecting 67 million people worldwide [1]. The disease damages the optic nerve due to elevated intraocular pressure (IOP) and can cause complete vision loss if untreated. IOP is commonly assessed using a single tonometric measurement, which provides a limited view since IOP fluctuates with circadian rhythms and physical activity. Continuous measurement can be achieved with an implanted monitor to improve treatment regiments, assess patient compliance to medication schedules, and prevent unnecessary vision loss. The most suitable implantation location is the anterior chamber of the eye, which is surgically accessible and out of the field of vision. The desired IOP monitor (IOPM) volume is limited to 1.5mm3 (0.5×1.5×2mm3)
Gregory Chen, Hassan Ghaed, Razi-ul Haque, Michael Wieckowski,