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该论文提出了一种用于主动隐形眼镜的3微瓦无线供电CMOS葡萄糖传感器,解决了非侵入式连续血糖监测的需求。通过利用泪液中的葡萄糖浓度与血糖的相关性,实现了低功耗、无线供电的片上传感系统。
The increase in the diabetes population makes glucose monitoring a pressing demand for clinical and continuous use. Non-invasive sensing would allow a painless, convenient solution compared to traditional skin-piercing glucose meters. Among various body fluids, tear fluid, which is correlated to the glucose concentration in blood [1], is directly accessible on the eye and can provide a unique opportunity to develop an interface between a sensor and the human body. The current technique is to collect tear fluid samples in capillary tubes and assay the samples for glucose ex situ using standard laboratory instrumentation. Integrating sensors into a contact lens would provide a way to continuously and reliably sense metabolites in tear fluids. We present an integrated wirelessly powered glucose sensor allowing a functional active system on a contact lens. This sensor IC consists of power management, readout circuitry, wireless communication interface, and energy-storage
Yu-Te Liao, Huanfen Yao, Babak Parviz, Brian Otis
University of Washington, Seattle, WA