⚡ 本页包含 AI 生成的分析内容,仅供参考
本文提出了一种基于CMOS集成电路与微流控通道的单细胞阻抗流式细胞仪,首次实现了非侵入性、高通量的3D流动单细胞实时分析。通过引入ΔΣ误差校正技术,提高了测量精度,为完整细胞分选器件的构建奠定了基础。
and haematology for the diagnosis and prognosis of disease. It involves the counting, identification and sorting of cells [1,2]. Conventional bulk measurements [3] require a large volume of blood, which is not desirable for the early detection of a disease, when only a very small percentage of cells contain evidence of the disease. In this paper, we propose, for the first time, a non-invasive and high-throughput single-cell analysis method using CMOS-integrated circuits in conjunction with a microfluidic channel as the first building block of a complete cell-sorting device. The description of the sensing scheme in the impedance cytometer is illustrated in Fig. 17.7.1. The device measures the spectral impedance of individual cells
Kang-Ho Lee , Jeonghun Nam , Sukhwan Choi , Hyunjung Lim ,
Sehyun Shin2, Gyu-Hyeong Cho1 1 1 2 2 1 2 KAIST, Daejeon, Korea Korea University, Seoul, Korea Flow cytometry is an essential cell analysis technology in clinical immunology