A Fully Intraocular 0.0169mm2/pixel 512-Channel Self-Calibrating Epiretinal Prosthesis in 65nm CMOS

📋 论文概要

本文提出了一款完全眼内植入的512通道自校准视网膜假体芯片，采用65nm CMOS工艺，像素面积仅为0.0169mm²，旨在提高空间分辨率以恢复功能性视觉感知。

💡 主要创新点

• 完全眼内植入设计，无需外部线缆，提高患者舒适度和系统可靠性。
• 自校准电路补偿工艺和失配，确保多通道一致性。
• 高密度512通道集成，像素面积小，实现高空间分辨率。

🏷 关键词

📄 原文摘要

Han-Chieh Chang1, Yu Zhao1, James Weiland2,3, Mark Humayun2,3, Yu-Chong Tai1, Azita Emami-Neyestanak1 California Institute of Technology, Pasadena, CA, Doheny Eye Institute, Los Angeles, CA, 3 University of Southern California, Los Angeles, CA 1 2 Since their conception and success in human trials, the flexibility and spatial resolution of retinal prostheses have been of major interest. Clinical studies have revealed that hundreds of channels are needed to restore functional visual perception [1], and more sophisticated waveforms present advantages over biphasic pulses [2]. Initial designs targeted stimulation current levels up to 1mA to ensure functionality. For such designs, an output compliance of >10V was required [2,3], and HV technologies were used at the expense of area and power consumption [2-6]. Human clinical trials have recently shown that implanted electrodes present a stimulus threshold as low as 50μA [1]. In addition,

👥 作者与机构

Manuel Monge1, Mayank Raj1, Meisam Honarvar-Nazari1,