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该论文提出了一种便携式微气相色谱系统,用于检测挥发性有机化合物,灵敏度达到15ppb,旨在解决非侵入性肺癌早期诊断中难以检测小尺寸异常组织的问题。
Po-Hung Kuo, Yen-Ming Huang, Wei-Che Hsieh, Shih-An Yu, Yufeng Jane Tseng , Wei-Cheng Tian, Si-Chen Lee, Shey-Shi Lu National Taiwan Univeristy, Taipei, Taiwan Existing non-invasive lung cancer diagnostic equipment has difficulty in detecting early stage lung cancer as abnormal tissue is smaller than 0.5cm in size. According to studies showing that volatile organic compounds (VOCs) from human breath gas can provide biomarkers for human disease, especially for lung cancer [1], a non-invasive method was developed to measure the exhaled air from cancer patients using chromatography-mass spectrometry (GC-MS). However, traditional GC-MS equipment is very expensive and requires specialists to operate. In this research we demonstrate a portable micro gas chromatography (μGC) system to overcome the limitations of conventional methods and realize small chips for big data. The system application scenario is shown in Figure 21.5.1. It includes four key
Te-Hsuen Tzeng, Chun-Yen Kuo, San-Yuan Wang, Po-Kai Huang,