A Smart CMOS Assay SoC for Rapid Blood Screening Test of Risk Prediction

📋 论文概要

该论文提出了一种基于CMOS技术的智能检测系统级芯片（SoC），用于快速血液筛查测试以预测疾病风险。解决了传统酶联免疫吸附试验（ELISA）检测耗时长、成本高的问题，适用于资源有限地区的即时筛查。

💡 主要创新点

• 提出了一种CMOS SoC实现快速血液检测，将检测时间从数小时缩短至即时。
• 集成了智能算法和传感器阵列，提高了检测灵敏度和可靠性。
• 实现了低成本、便携式设计，适合大规模快速筛查应用。

🏷 关键词

📄 原文摘要

Taiwan University Hospital, Taipei, Taiwan 1 2 Rapid blood test is essential to disease control, risk assessment and point-ofcare testing. Conventional enzyme-linked immunosorbent assay (ELISA) requires several hours or even days to get meaningful results. However, to some fierce contagious diseases, such as Ebola and SARS, the contagion can spread so fast that an instant and massive screening test is needed. A CMOS assay system-on-chip (SoC) offering a fast and cheap disease screening tool can be very helpful in the place where the medical resources are limited and the test is too costly to afford. Unlike the previously proposed CMOS biomolecular detection based on direct detection [1], a sandwiched assay detection protocol

👥 作者与机构

Po-Hung Kuo1, Jui-Chang Kuo1, Hsiao-Ting Hsueh1, Jian-Yu Hsieh1,

Yi-Chun Huang1, Tao Wang2, Yen-Hung Lin3, Chih-Ting Lin1, Yao-Joe Yang1, Shey-Shi Lu1 National Taiwan Univeristy, Taipei, Taiwan, Chang Gung University, Taoyuan, Taiwan, 3 National