A 966-Electrode Neural Probe with 384 Configurable Channels in 0.13µm SOI CMOS

📋 论文概要

本文提出了一种采用0.13µm SOI CMOS工艺的966电极神经探针，具有384个可配置通道，用于同时记录动作电位和局部场电位信号。该探针通过高密度电极阵列和可配置通道设计，实现了大规模神经信号记录并最小化组织损伤。

💡 主要创新点

• 实现了966个电极的高密度集成，显著提升空间分辨率。
• 384个通道可灵活配置，支持同时记录动作电位和局部场电位。
• 采用0.13µm SOI CMOS工艺，降低噪声并提高集成度。

🏷 关键词

📄 原文摘要

Bogdan Raducanu1,2, Marco Ballini1, Alexandru Andrei1, Simone Severi1, Marleen Welkenhuysen1, Chris Van Hoof1,2, Silke Musa1, Refet Firat Yazicioglu1 imec, Leuven, Belgium, 2KU Leuven, Heverlee, Belgium 1 In vivo recording of neural action-potential (AP) and local-field-potential (LFP) signals requires the use of high-resolution penetrating probes. Driven by the need for large-scale recording and minimal tissue damage, a technology roadmap has been defined for next-generation probes aiming to maximize the number of recording sites while minimizing the probe dimensions [1]. In this paper we present a 384-channel configurable active neural probe for high-density recording which implements in situ buffering under each electrode to minimize the crosstalk between adjacent metal lines along the shank and other parasitic effects inherent to traditional passive probes [2]. Up to 966 selectable, neuron-sized electrodes

👥 作者与机构

Carolina Mora Lopez1, Srinjoy Mitra1, Jan Putzeys1,