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ISSCC 2016Session 28 · BIOLOGICAL SENSORS FOR POINT OF CAREMedical & Bio

A Handheld 50pM-Sensitivity Micro-NMR CMOS Platform with B-Field Stabilization for Multi-Type Biological/Chemical Assays

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📋 论文概要

该论文提出了一种手持式微核磁共振(NMR)CMOS平台,通过B场稳定技术实现了50pM的灵敏度,用于多种生物/化学检测。解决了传统NMR仪器体积大、成本高的问题,适用于即时检测场景。

💡 主要创新点

核心指标
50pM灵敏度
重要性
发表年份
ISSCC 2016

🏷 关键词

微核磁共振CMOS平台即时检测B场稳定磁性纳米颗粒

📄 原文摘要

Franco Maloberti2, Rui P. Martins1,4 University of Macau, Macau, China, University of Pavia, Pavia, Italy, 3 University of Glasgow, Glasgow, United Kingdom, 4 Instituto Superior Tecnico, Lisbon, Portugal 1 2 Point-of-use (PoU) biological/chemical assays are aimed to transform bulky laboratory instruments into easy-to-use lab-on-a-chip platforms, bringing down the cost, size, and sample-use by orders of magnitude [1,2]. Micro-Nuclear Magnetic Resonance (NMR) is a trail-blazing tool for target pinpointing, by utilizing functionalized magnetic nanoparticles (MNPs) as the probe [3]. Screening by micro-NMR is repeatable, versatile and low-cost as it is label- and washingfree for the samples, and immobilization-free for the electrodes. Herein, a high-sensitivity micro-NMR CMOS platform with magnetic (B)-field stabilization and thermal management is reported (Fig. 28.1.1). This handheld tool unifies

👥 作者与机构

Ka-Meng Lei1, Hadi Heidari2,3, Pui-In Mak1, Man-Kay Law1,

分类:Medical & Bio · 年份:ISSCC 2016