CMOS Biosensor IC Focusing on Dielectric Relaxations of Biological Water with 120GHz and 60GHz Oscillator Arrays

📋 论文概要

本文提出了一种基于CMOS工艺的生物传感器芯片，利用120GHz和60GHz振荡器阵列探测生物水的介电弛豫特性。通过优化布局和分时复用技术，降低了功耗和频率偏差，实现了高灵敏度检测。

💡 主要创新点

• 首次在CMOS芯片上集成120GHz和60GHz振荡器阵列，用于生物水的介电弛豫测量。
• 通过排除外围单元改善布局各向异性，将频率偏差从0.07GHz和0.03GHz分别降低。
• 采用分时复用方案，非选中单元关闭以降低总功耗，120GHz单元仅29mA@1.2V。

🏷 关键词

📄 原文摘要

are reduced to 0.07GHz (resp. 0.03GHz) if we exclude the 52 elements (resp. 44 elements) on the periphery that exhibit larger deviations due to the anisotropy of the layout. A selected 120GHz (resp. 60GHz) element draws 29mA (resp. 10.1mA) from a 1.2V power supply; other unselected elements are disabled to reduce the total power consumption. The oscillator phase noise and the gating time determine the sensitivity. When we count the 100MHz output by setting the division ratio to 1200 (resp. 600) for the 120GHz (resp. 60GHz) element, we obtained the smallest input-referred SD of 0.50MHz (resp. 0.21MHz) or 4.2ppm (resp. 3.5ppm) for a 5ms gating time. 1 2 The water present in the close vicinity of biomolecules is particularly relevant to

👥 作者与机构

Takeshi Mitsunaka1, Nobuyuki Ashida1, Akira Saito1,

Kunihiko Iizuka1, Tetsuhito Suzuki2, Yuichi Ogawa2, Minoru Fujishima3 SHARP, Tenri, Japan, Kyoto University, Kyoto, Japan, 3 Hiroshima University, Higashi-Hiroshima, Japan air and water