⚡ 本页包含 AI 生成的分析内容，仅供参考
该论文介绍了高通量DNA测序技术的发展历程，从Sanger测序到454生命科学的大规模并行测序，推动了基因组学在研究和医学中的应用。
that biological information was encoded in DNA as a sequence of chemical building-block “letters”, developing technology for reading (or “sequencing”) this chemical code has been fundamental to advances in biology and medicine. Techniques that first enabled this were invented by Sanger in 1978, and were taken to massively parallel form by 454 Life Sciences in 2003 [1]. This ushered in the current or “next-gen” era of genome sequencing technologies for research, medicine, and the emerging field of Genomic-Personalized Medicine, in which healthcare is more fully informed by the individuals’ personal genetic makeup. Five years after the Human-Genome Project, very little had changed in sequencing technology until my team at 454 Life Sciences pioneered (and was
Jurassic Park, Neanderthal, Moore, and You, 1
Jonathan Rothberg, Founder, 4Catalyzer and Adjunct Professor of Genetics, Yale School of Medicine, New Haven, CT Since Watson and Crick’s 1953 landmark discovery