⚡ 本页包含 AI 生成的分析内容,仅供参考
该论文提出了一种异质集成的CMOS-石墨烯传感器阵列,用于多巴胺检测。它解决了现有碳微纤维电极体积大、空间分辨率低的问题,实现了高空间分辨率的实时监测。
for advancing our knowledge of pathological disorders such as drug addiction, Parkinson’s disease, and schizophrenia. Currently, fast-scan cyclic voltammetry (FSCV) with carbon microfiber (CMF) electrodes is the method of choice in neuroscience labs for monitoring the concentration of phasic (transient) DA release. This method offers sub-second temporal resolution and high specificity because the signal of interest occurs at a known potential. However, existing CMF electrodes are bulky, limiting the spatial resolution to single-site measurements. Further, they are produced through manual processes (e.g. cutting CMFs under optical microscope), thus introducing significant device variability [1]. Lastly, when long
Bayan Nasri, Ting Wu, Abdullah Alharbi, Mayank Gupta,
Ramkumar RanjitKumar, Sunit Sebastian, Yue Wang, Roozbeh Kiani, Davood Shahrjerdi New York University, Brooklyn, NY Understanding dopamine (DA) signaling in the brain is essential