A Sub-mm3 Wireless Implantable Intraocular Pressure Monitor Microsystem

📋 论文概要

该论文提出了一种完全无线的亚立方毫米级眼压监测微系统，集成了供电线圈、遥测天线、压阻式MEMS压力传感器和180nm CMOS压力传感芯片，用于植入眼前房以实时监测眼压，解决传统眼压测量无法捕捉昼夜变化和体位依赖性的问题。

💡 主要创新点

• 实现了亚立方毫米级（<1mm³）的完全无线植入式眼压监测微系统，体积极小。
• 集成了供电线圈、遥测天线、MEMS传感器和CMOS芯片于一体，实现无线供电和数据传输。

🏷 关键词

📄 原文摘要

intraocular pressure (IOP) in the anterior chamber of the eye can damage the optic nerve causing irreversible blindness [1]. An IOP monitoring microsystem (IMM) implanted in the interior chamber of the eye is required to take frequent IOP measurements to account for its diurnal variation and dependency on the body posture, which is not possible with the widely used tonometric measurement [2-4]. We present a fully wireless sub-mm3 IMM that comprises a powering coil, a telemetry antenna, a piezoresistive MEMS pressure sensor, and a 180nm CMOS pressure sensing IC (Fig. 21.3.1). The volume of this IMM is limited to 0.38mm3 for the studies on rodents prior to the human trials, which is 4× lower than the previous state-of-the-art IMM that occupies 1.5mm3 and targets only human eye

👥 作者与机构

Hansraj Bhamra, Jui-Wei Tsai, Yu-Wen Huang, Quan Yuan, Pedro Irazoqui

Purdue University, West Lafayette, IN Glaucoma is an eye disease, where the elevated level of