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ISSCC 2017Session 27 · BIOMEDICAL CIRCUITSMedical & Bio0.18μm CMOS

A 2.8µW 80mVpp-Linear-Input-Range 1.6GΩ-Input Impedance Bio-Signal Chopper Amplifier Tolerant to Common-Mode Interference up to 650mVpp

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📋 论文概要

本文提出了一种用于神经记录的斩波放大器,能够容忍高达80mVpp的差分模式和650mVpp的共模干扰,同时保持1.6GΩ的输入阻抗和2.8μW的低功耗,解决了闭环神经调控中刺激伪影导致前端饱和的问题。

💡 主要创新点

核心指标
2.8μW功耗,80mVpp线性输入范围,1.6GΩ输入阻抗
工艺节点
0.18μm CMOS
重要性
发表年份
ISSCC 2017

🏷 关键词

神经记录斩波放大器共模干扰抑制

📄 原文摘要

Closed-loop neuromodulation with simultaneous stimulation and sensing is desired to administer therapy in patients suffering from drug-resistant neurological ailments. However, stimulation generates large artifacts at the recording sites, which saturate traditional front-ends. The common-mode (CM) artifact can be ~500mV, and the differential-mode (DM) artifact is 50 to 100mV. This work presents a neural recording chopper amplifier that can tolerate 80mVpp DM and 650mVpp CM artifacts in a signal band of 1Hz to 5kHz. To digitize a 2mVpp neural signal to 8b accompanied by an 80mVpp DM artifact requires a linearity of 80dB. Neural recording front-ends also need to function within a power budget of 3 to 5μW/ch, input-referred noise of 4 to 8μVrms, DC input impedance Zin>1GΩ and high-pass cutoff of 1Hz [1,2]. Prior work has addressed power and noise [26], but has low Zin and limited input signal range, making them incapable of

👥 作者与机构

Hariprasad Chandrakumar, Dejan Marković

University of California, Los Angeles, CA

分类:Medical & Bio · 年份:ISSCC 2017