A Trimodal Wireless Implantable Neural Interface System-on-Chip

📋 论文概要

该论文提出了一种三模态无线植入式神经接口系统芯片，集成了电刺激、神经记录和光遗传学调制功能，旨在实现闭环神经调控，提高治疗效果并降低功耗。

💡 主要创新点

• 首次将电刺激、神经记录和光遗传学三种模态集成在单一芯片上，实现多功能神经接口。
• 采用无线供电和双向数据传输，支持植入式设备的长期稳定工作。
• 通过低功耗电路设计和反馈机制优化，降低系统能耗同时提升刺激精度。

🏷 关键词

📄 原文摘要

5Bionic Sciences, Atlanta, GA 1 3 Implantable biomedical devices (IMDs) capable of injecting a designated current into target neural tissue to modulate neural activity have been proven therapeutically effective. The next generation of IMDs is expected to sense changes in the evoked neural activities, allowing recorded data to be used as feedback mechanism to adjust stimulation parameters/patterns, making these systems even more effective while reducing power consumption [1]. Recently, optogenetic neuromodulation with distinct advantages of cell-type specificity, high temporal precision, and rapid reversibility has been added to researchers’ arsenal and resulted in the development of IMDs with optical stimulation capability [2,3].

👥 作者与机构

Yaoyao Jia1, Ulkuhan Guler2, Yen-Pang Lai3, Yan Gong4, Arthur Weber4,

Wen Li4, Maysam Ghovanloo5 North Carolina State University, Raleigh, NC, 2WPI, Worcester, MA Georgia Institute of Technology, Atlanta, GA 4 Michigan State University, East Lansing, MI,