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ISSCC 2021Session 18 · BIOMEDICAL DEVICES, CIRCUITS, AND SYSTEMSMedical & Bio

An Integrated Thermal Actuation/Sensing Array with Stacked Oscillators for Efficient and Localized Heating of Magnetic Nanoparticles with Sub-Millimeter Spatial Resolution efficiency and loop gain. A smaller VGS reduces the conduction angle in the large-signal operation for better energy efficiency while compromising the loop gain at startup. With 0.5V VGS, the simulated efficiency is >45%, and the loop gain is >2.3 across the entire frequency tuning range.

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📋 论文概要

本文提出一种集成热驱动/传感阵列,采用堆叠振荡器实现高效局部加热磁性纳米颗粒,通过电热反馈控制振荡幅度,并验证了长期稳定性。解决了传统方法中加热效率低和局部控制不足的问题。

💡 主要创新点

核心指标
RF摆幅>19.5Vpp(四堆叠), >26.5Vpp(五堆叠); 频率范围1.44-1.95GHz; 连续六天摆幅稳定
重要性
发表年份
ISSCC 2021

🏷 关键词

热驱动阵列堆叠振荡器磁纳米颗粒加热电热反馈生物医学

📄 原文摘要

the fourth row of the array and capacitively coupled to the oscillator outputs. The measured maximum RF swing is >19.5Vpp for the four-stacked oscillator and >26.5Vpp for the five-stacked oscillator from 1.44 to 1.95GHz (Fig. 18.3.3), which is very close to our simulation. During a continuous six-day monitoring, the oscillation swing remains constant, verifying the safe operation of stacked transistors. By reducing the biasing voltage of the tail transistor (Vtail), the oscillation amplitude can be backed-off (Fig. 18.3.3). This property is used in the electro-thermal feedback to lower the dc power if a lower temperature is desired. Rice University, Houston, TX Magnetic nanoparticles (MNP) can generate localized thermal stress in response to an external ac magnetic field, offering unique opportunities for a wide range of biomedical applications. For example, hyperthermia cancer therapy, which raises the local

👥 作者与机构

Yingying Fan, Linlin Zhang, Qingbo Zhang, Gang Bao, Taiyun Chi, To characterize the performance of stacked oscillators, open-drain buffers are added to

分类:Medical & Bio · 年份:ISSCC 2021