⚡ 本页包含 AI 生成的分析内容，仅供参考
该论文提出一种机械柔性可植入神经接口，集成了计算成像和光遗传刺激功能，面积5.4×5.4mm。它替代了传统大型显微镜，实现了单细胞分辨率的神经活动记录与刺激。
Jacob T. Robinson3, Ashok Veeraraghavan3, Kenneth L. Shepard1 Columbia University, New York, NY University of Washington, Seattle, WA 3 Rice University, Houston, TX 1 2 *Equally-Credited Authors (ECAs) The advent of genetically encoded voltage and calcium indicators and optogenetic probes has unlocked unprecedented capabilities, including near-single-action-potential recording and stimulation with cell-type specificity. Optical functional imaging and optogenetics are delegated today primarily to large and expensive microscopes based on free-space optics. Integrating the microscope functionality into an implantable form factor remains an elusive goal. As a first step towards developing such a device, a variety of head-mounted “miniscopes” have been demonstrated [1]. Using conventional lensbased optics, however, these devices consume considerable volume (more than 2cm3) to support field of views (FoVs) of sub-mm2. To achieve a truly implantable microscope,
Sajjad Moazeni*1,2, Eric H. Pollmann*1, Vivek Boominathan3, Filipe A. Cardoso1,