A 22µW Peak Power Multimodal Electrochemical Sensor Interface IC for Bioreactor Monitoring

📋 论文概要

本文提出了一种用于生物反应器监测的22µW峰值功耗多模态电化学传感器接口芯片，能够同时测量温度、酸度、氧化还原电位、溶解氧、离子浓度和代谢物等多种参数，解决了传统分立传感器功耗高、体积大的问题。

💡 主要创新点

• 实现了22µW超低峰值功耗的多模态电化学传感接口，适用于生物反应器长期监测。
• 集成了多种传感模式（温度、pH、ORP、溶解氧、离子、代谢物），无需外部多芯片方案。
• 采用低功耗电路设计技术，在保持精度的同时显著降低功耗。

🏷 关键词

📄 原文摘要

The Netherlands 1 2 Bioreactors are employed in many industries like food, beverage, chemical, and biopharmaceutical to grow biologically active compounds. Bioreactors range in size from large industrial tanks for manufacturing to small single-use vessels for process flow development or research purposes like vaccine discovery. To ensure optimal bioreactor operation, there is a need to monitor various parameters, including temperature, acidity, oxidation-reduction potential (ORP), dissolved oxygen, ion concentrations, and other metabolites like glucose and lactate. Usually, these are measured with glass probes and tubes fed into the bioreactor via holes in the lid or side, resulting in bulky and complex

👥 作者与机构

Qiuyang Lin1, Wim Sijbers1, Christina Avdikou1, Didac Gomez1,2,

Dwaipayan Biswas1, Sneha Sneha3, Anastasios Malissovas3, Bernardo Tacca3, Nick Van Helleputte1 imec, Leuven, Belgium, now with MPS Spain, Barcelona, Spain 3 imec - Holst Centre, Eindhoven