A 9mW Ultrasonic Through Transmission Transceiver for Non-Invasive Intracranial Pressure Sensing

📋 论文概要

该论文提出了一种9mW的超声透射收发器，用于无创颅内压（ICP）传感。通过监测ICP波形变化（尤其是P2/P1比值），解决临床上有创ICP监测的侵入性问题，实现低功耗连续监测。

💡 主要创新点

• 采用超声透射方式实现无创ICP传感，避免了传统有创传感器的感染风险。
• 实现9mW超低功耗收发器，适用于长期便携监测。
• 通过P2/P1波形比值评估脑顺应性，提供临床相关指标。

🏷 关键词

📄 原文摘要

(ICP) measures the pressure exerted by fluids and tissues inside the skull, typically 7-15mmHg for healthy adults. Conditions such as traumatic brain injury, hydrocephalus, and intracranial hemorrhage often cause elevated ICP (>20mmHg), which is life-threatening and requires immediate medical interventions. These conditions also lead to changes in the ICP waveform morphology, especially an increased P2/P1 amplitude ratio, reflecting compromised cerebral compliance [1] (Fig. 17.11.1, top left). Clinicians routinely use ICP monitoring in neurovascular intensive care units (neuro-ICUs) because it provides actionable and timely information for patient care – the recovery of the ICP waveform morphology often suggests effective medical interventions. Conventionally, neurosurgeons measure ICP through two invasive methods (Fig. 17.11.1,

👥 作者与机构

Gerald Topalli1, Yingying Fan1, Matt Y. Cheung1, Ashok Veeraraghavan1,

Mohammad Hirzallah2, Taiyun Chi1 Rice University, Houston, TX Baylor Collage of Medicine, Houston, TX 1 2 Intracranial pressure