A 2.7ps-ToF-Resolution and 12.5mW Frequency-domain NIRS Readout IC with Dynamic Light Sensing Frontend and Cross-Coupling-Free Inter-Stabilized Data Converter

📋 论文概要

提出了一种频域近红外光谱读出集成电路，通过动态光传感前端和交叉耦合技术实现了2.7ps飞行时间分辨率和12.5mW的低功耗。解决了传统连续波NIRS系统只能记录光强、无法分离吸收和散射系数的问题，实现了绝对代谢物浓度的量化。

💡 主要创新点

• 采用动态光传感前端，实现高灵敏度光检测并降低功耗
• 引入交叉耦合技术，提升飞行时间分辨率至2.7ps
• 集成频域NIRS读出方案，支持吸收和散射系数的分离测量

🏷 关键词

📄 原文摘要

United Imaging Microelectronics Technology, Shanghai, China 4 Shanghai Mental Health Center, Shanghai, China 1 2 The non-invasive quantification of metabolite concentration is of significant importance in the fields of medical diagnosis and monitoring. Functional near-infrared spectroscopy (NIRS) offers a promising optical solution for this purpose. However, conventional continuous-wave (CW) NIRS systems only record light intensity, limiting analysis of optical absorption (μa) and reduced scattering (μs’) coefficient fluctuations in substances [1-2]. This hinders obtaining absolute metabolite concentrations, limiting the technology’s utility. Frequency-domain (FD) NIRS emits intensity-modulated light into human tissues, allowing simultaneous measurement of changes in optical intensity loss

👥 作者与机构

Zhouchen Ma1, Yuxiang Lin1, Cheng Chen1, Xiang’ao Qi1, Yongfu Li1,

Kea-Tiong Tang2, Fa Wang3, Tianhong Zhang4, Guoxing Wang1, Jian Zhao1 Shanghai Jiao Tong University, Shanghai, China National Tsing Hua University, Hsinchu, Taiwan 3 Shanghai