⚡ 本页包含 AI 生成的分析内容,仅供参考
该论文提出了一种用于视网膜植入的闭环100通道高度可扩展系统,集成了基于模拟能量检测的自适应阈值尖峰检测电路,功耗仅为1.02μW,旨在解决视网膜退化患者视觉恢复中的刺激效率与功耗问题。
Intraocular stimulators have demonstrated promise in treating patients with retinal degeneration (e.g., age-related macular degeneration) by restoring visual input to the compromised retina. This is done by capturing images with an electronic photosensor and subsequently stimulating remaining retinal cells, (e.g., bipolar, ganglion), thus bypassing the dysfunctional photoreceptors. Figure 33.5.1 (top, left) shows sub- and epi-retinal electrical stimulators, with the former potentially offering more natural vision restoration and the latter being less invasive. Regardless, a common issue with reported electrical retinal stimulators is their lack of cell-type specificity, which results in stimulating both ON and OFF pathways in the retinal network, as illustrated by the simulation results shown in Fig. 33.5.1 (left). This leads to contradictory messages to the brain, resulting in constrained visual perception, regardless of spatial resolution.
Tayebeh Yousefi, Georg Zoidl, Hossein Kassiri
York University, Toronto, Canada