An 80×80μm2/Pixel 55.48dB-Wide-DR 400-Pixel Subretinal Prosthesis SoC with Power-Aware Light Adaptation and Charge-Recycling Local Dynamic Supply

📋 论文概要

提出了一款光适应视网膜假体（LARP）SoC，通过功率感知光适应实现了55.48dB的宽光感动态范围，并采用像素聚类技术将像素尺寸缩小至80×80μm²，提高了刺激空间分辨率。电荷回收局部动态供电方案使刺激能量降低34%，经图像投影测试和离体小鼠视网膜细胞实验验证了有效性。

💡 主要创新点

• 采用功率感知光适应技术，实现55.48dB的宽动态范围，适应不同光照条件。
• 通过像素聚类实现80×80μm²紧凑像素尺寸，提升400像素阵列的空间分辨率。

📄 原文摘要

Abstract We propose a light-adaptive retinal prosthesis (LARP) SoC, which employs power-aware light adaptation achieving a wide light-sensing DR of 55.48dB. Pixel clustering enables a compact pixel size of 80×80μm2, enhancing the stimulation spatial resolution. The charge- recycling local dynamic supply scheme enables up to a 34% reduction in stimulation energy. Image projection tests and ex vivo experiments using mouse retinal cells demonstrate the effectiveness of the LARP SoC. Numerous studies have investigated direct retinal cell stimulation as a strategy to better understand the retinal network and restore vision [1,2]. A retinal prosthesis (RP) systemon-chip (SoC) elicits visual perception by electrically stimulating retinal cells, representing a promising therapeutic option for age-related macular degeneration (AMD) and retinal pigment degeneration. Other approaches, such as optogenetics [3] and visual cortex

👥 作者与机构

Kyeongho Eom1, Hyun-Su Lee1, Minju Kim2, Maesoon Im2, Hyung-Min Lee1

Korea University, Seoul, Korea, 2Korea Institute of Science and Technology, Seoul, Korea